XCP-D : A Robust Postprocessing Pipeline of fMRI data


This fMRI post-processing and noise regression pipeline is developed by the Satterthwaite lab at the University of Pennslyvania (XCP; eXtensible Connectivity Pipeline) and Developmental Cognition and Neuroimaging lab at the University of Minnesota (-DCAN) for open-source software distribution.


XCP-D paves the final section of the reproducible and scalable route from the MRI scanner to functional connectivity data in the hands of neuroscientists. We developed XCP-D to extend the BIDS and NiPrep apparatus to the point where data is most commonly consumed and analyzed by neuroscientists studying functional connectivity. Thus, with the development of XCP-D, data can be automatically preprocessed and analyzed in BIDS format, using NiPrep-style containerized code, all the way from the from the scanner to functional connectivity matrices.

XCP-D picks up right where fMRIprep ends, directly consuming the outputs of fMRIPrep. XCP-D leverages the BIDS and NiPrep frameworks to automatically generate denoised BOLD images, parcellated time series, functional connectivity matrices, and quality assessment reports. XCP-D can also process outputs from: NiBabies, DCAN and Minimally preprocessed HCP data.


See the documentation for more details.

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